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Introduction to hesim9 months ago
Overview | Treatment strategies, target population, and model structure | Parameterization | Disease progression | Costs and utility | Simulation | Constructing an economic model | Disease model | Cost and utility models | Combining the disease progression, cost, and utility models | Simulating outcomes | Decision analysis | Next steps
Time inhomogeneous Markov cohort models9 months ago
Overview | Model setup | Model parameters | Estimates from the literature | Transition probabilities | Utility | Costs | Combining all parameters | Random number generation | Transformed parameters | Simulation | Constructing the economic model | Simulating outcomes | Health state probabilities | Costs and QALYs | Decision analysis | Subgroup analysis | Overall | Appendix | Transition probabilities from a Weibull survival model | Direct construction of transition matrices | Input data
Time inhomogeneous Markov individual-level models4 years ago
Overview | Model setup | Parameters | Transitions | Estimates from literature | Transition 1 | Transition 2 | Transition 3 | Transition 4 | Transition 5 | Transition 6 | Transition 7 | Transition 8 | Multi-state model | Utility and costs | Simulation | Constructing the model | Disease model | Cost and utility models | Combining the models | Simulating outcomes | Disease progression | Costs and QALYs | Decision analysis
Markov and semi-Markov multi-state models5 years ago
Overview | An example 3-state model | Parameter estimation | Multi-state model | Utility and costs | Simulation | Constructing the economic model | Disease model | Utility and cost models | Combining the disease progression, cost, and utility models | Simulating outcomes | Disease progression | Costs and QALYs | Decision analysis
Markov models with multinomial logistic regression5 years ago
Overview | An example 3-state model | Parameter estimation | Multinomial logit model for transition probabilities | Utility and costs | Simulation | Constructing the economic model | Disease model | Utility and cost models | Combining the disease progression, cost, and utility models | Simulating outcomes | Disease progression | Costs and QALYs | Decision analysis
Partitioned survival models5 years ago
Overview | An example 4-state PSM | Parameter estimation | Survival models | Utility and cost models | Simulation | Constructing the economic model | Combining the statistical models | Simulating outcomes | Simulating survival curves | Simulating health state probabilities | Simulating costs and QALYs | Decision analysis
Simple Markov cohort model5 years ago
Overview | Model setup | Model parameters | Estimates from the literature | Random number generation | Transformed parameters | Simulation | Constructing the economic model | Simulating outcomes | Health state probabilities | Costs and QALYs | Decision analysis | Appendix: Dirichlet distribution
Cost-effectiveness analysis5 years ago
Overview | Framework | Probabilistic sensitivity analysis | Decision analysis | Incremental cost-effectiveness ratio (ICER) | Cost-effectiveness plane | Cost-effectiveness acceptability curves (CEAC) | Simultaneous comparison | Pairwise comparison | Cost-effectiveness acceptability frontier (CEAF) | Value of perfect information | Value of individualized care | References