Package: hesim Type: Package Title: Health Economic Simulation Modeling and Decision Analysis Version: 0.5.8 Authors@R: c( person("Devin", "Incerti", , "devin.incerti@gmail.com", role = c("aut", "cre")), person("Jeroen P.", "Jansen", role = "aut"), person("Mark", "Clements", role = "aut"), person(given = "R Core Team", role = "ctb", comment="hesim uses some slightly modified C functions from base R") ) Description: A modular and computationally efficient R package for parameterizing, simulating, and analyzing health economic simulation models. The package supports cohort discrete time state transition models (Briggs et al. 1998) , N-state partitioned survival models (Glasziou et al. 1990) , and individual-level continuous time state transition models (Siebert et al. 2012) , encompassing both Markov (time-homogeneous and time-inhomogeneous) and semi-Markov processes. Decision uncertainty from a cost-effectiveness analysis is quantified with standard graphical and tabular summaries of a probabilistic sensitivity analysis (Claxton et al. 2005, Barton et al. 2008) , . Use of C++ and data.table make individual-patient simulation, probabilistic sensitivity analysis, and incorporation of patient heterogeneity fast. URL: https://hesim-dev.github.io/hesim/, https://github.com/hesim-dev/hesim BugReports: https://github.com/hesim-dev/hesim/issues License: GPL-3 LazyData: true LinkingTo: Rcpp, RcppArmadillo Depends: R (>= 3.5.0) Imports: data.table, flexsurv, ggplot2, MASS, msm, Rcpp (>= 0.12.16), R6, stats, survival Suggests: covr, kableExtra, knitr, magrittr, mstate, nnet, numDeriv, pracma, rmarkdown, scales, testthat, truncnorm VignetteBuilder: knitr Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Config/pak/sysreqs: libicu-dev Repository: https://hesim-dev.r-universe.dev Date/Publication: 2026-01-16 23:41:05 UTC RemoteUrl: https://github.com/hesim-dev/hesim RemoteRef: HEAD RemoteSha: 676630b6247c8fedec5deed8f23a157e722b392c NeedsCompilation: yes Packaged: 2026-06-16 11:24:57 UTC; root Author: Devin Incerti [aut, cre], Jeroen P. Jansen [aut], Mark Clements [aut], R Core Team [ctb] (hesim uses some slightly modified C functions from base R) Maintainer: Devin Incerti